The season-opening Qatar MotoGP, scheduled to take place on March 8, was canceled Sunday because of the spread of the coronavirus, the international motorcycling federation (FIM) announced.
"Due to Qatar travel restrictions brought into force affecting passengers from Italy [among other countries], the premier class will not race at the Losail circuit," the FIM said.
However, the Moto2 and Moto3 world championship races will go ahead as planned at the desert track as riders and teams were already in the Gulf state preparing for the event with winter testing.
As the coronavirus has spread, Italy has become the hardest-hit European country with 34 deaths and over 1,600 people infected.
"As of today, all passengers arriving at Doha on direct flights from Italy, or having been in Italy in the past two weeks, will be taken straight to quarantine for a minimum of 14 days," added the FIM.
"Italy clearly plays a vital role in the championship and in the MotoGP class - both on track and off - and therefore the decision has been taken to cancel premier class competition."
Six riders in the elite class are Italian - seven-time MotoGP world champion Valentino Rossi, 2019 runner-up Andrea Dovizioso, Danilo Petrucci, Francesco Bagnaia, Franco Morbidelli and Andrea Iannone. Ducati and Aprilia are leading Italian manufacturers.
MotoGP riders and teams were in Qatar from February 22 to 24 for the final session of winter testing.
Qatar was to be the first of a 20-race MotoGP season and it becomes the latest motorsports event cancelled because of the spread of coronavirus.